Halneuron®
The non-opiod painkiller

Presentations

Scientific Publications

List of Publications with Author(s) from WEX

Marcil J, Walczak JS, Guindon J, Ngoc AH, Lu S, Beaulieu P. Antinociceptive effects of tetrodotoxin (TTX) in rodents.

Br J Anaesth. 2006 Jun;96(6):761-8.

Hagen NA, Fisher KM, Lapointe B, du Souich P, Chary S, Moulin D, Sellers E, Ngoc AH; Canadian Tetrodotoxin Study Group. An open-label, multi-dose efficacy and safety study of intramuscular tetrodotoxin in patients with severe cancer-related pain.

J Pain Symptom Manage. 2007 Aug;34(2):171-82.

Guzmán A, Fernández de Henestrosa AR, Marín AP, Ho A, Borroto JI, Carasa I, Pritchard L. Evaluation of the genotoxic potential of the natural neurotoxin Tetrodotoxin (TTX) in a battery of in vitro and in vivo genotoxicity assays.

Mutat Res. 2007 Dec 1;634(1-2):14-24.

Hagen NA, du Souich P, Lapointe B, Ong-Lam M, Dubuc B, Walde D, Love R, Ngoc AH; Canadian Tetrodotoxin Study Group. Tetrodotoxin for moderate to severe cancer pain: a randomized, double blind, parallel design multicenter study.

J Pain Symptom Manage. 2008 Apr;35(4):420-9.

Hagen NA, Lapointe B, Ong-Lam M, Dubuc B, Walde D, Gagnon B, Love R, Goel R, Hawley P, Ngoc AH, du Souich P. A multicentre open-label safety and efficacy study of tetrodotoxin for cancer pain.

Curr Oncol. 2011 Jun;18(3):e109-16.

Berde CB, Athiraman U, Yahalom B, Zurakowski D, Corfas G, Bognet C. Tetrodotoxin-bupivacaine-epinephrine combinations for prolonged local anesthesia.

Mar Drugs. 2011 Dec;9(12):2717-28.

Hagen NA, Cantin L, Constant J, Haller T, Blaise G, Ong-Lam M, du Souich P, Korz W, Lapointe B. Tetrodotoxin for Moderate to Severe Cancer-Related Pain: A Multicentre, Randomized, Double-Blind, Placebo-Controlled, Parallel-Design Trial.

Pain Res Manag. 2017;2017:7212713.

Kavoosi M, O’Reilly TE, Kavoosi M, Chai P, Engel C, Korz W, Gallen CC, Lester RM. Safety, Tolerability, Pharmacokinetics, and Concentration-QTc Analysis of Tetrodotoxin: A Randomized, Dose Escalation Study in Healthy Adults.

Toxins (Basel). 2020 Aug 9;12(8):511.

Goldlust SA, Kavoosi M, Nezzer J, Kavoosi M, Korz W, Deck K. Tetrodotoxin for Chemotherapy-Induced Neuropathic Pain: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Dose Finding Trial.

Toxins (Basel). 2021 Mar 25;13(4):235.

List of Publications without Authors from WEX

González-Cano R, Ruiz-Cantero MC, Santos-Caballero M, Gómez-Navas C, Tejada MÁ, Nieto FR. Tetrodotoxin, a Potential Drug for Neuropathic and Cancer Pain Relief?

Toxins. 2021 Jul 12;13(7):483.

Berde CB, Athiraman U, Yahalom B, Zurakowski D, Corfas G, Bognet C. Tetrodotoxin-bupivacaine-epinephrine combinations for prolonged local anesthesia.

Mar Drugs. 2011 Dec;9(12):2717-28.