A Randomized, Double-Blind, Dose-Finding, Placebo Controlled, Phase II Multicenter Study of Tetrodotoxin in the Treatment of Chemotherapy Induced Neuropathic Pain.

The study was designed to determine the safety and effectiveness of various regimens of TTX in patients with neuropathic pain caused by chemotherapy. In addition, the time to the start and the duration of the pain relief, whether TTX helps in reducing the use of other painkillers, and whether TTX helps in reducing symptoms other than pain.